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5-Hydroxyindoleacetic Acid, 24-Hour Urine

5-Hydroxyindoleacetic Acid, 24-Hour Urine

Alternate Test Name

5-HIAA, 24 Hour Urine

Epic Mnemonic
Sunquest Mnemonic

LAB352
UHIAAB

Category

Sendouts

Methodology

Liquid Chromatography-Mass Spectrometry

Test Performance Schedule

Monday - Friday

Result Availability

2 - 3 days

Specimen Required

Container

24-hour Urine Container, no preservative
Note:
Additionof 50% acetic acid prior to start of collection is preferred but not required. Refrigeration during and after urine collection is an acceptable means of urine preservation.
If adding preservative:
Add 25 mL 50% acetic acid at start of collection
Children under 5 years, add 15 mL 50% acetic acid

Volume

Entire timed urine

Collection Instructions

• To begin collection of timed specimen, have patient urinate, noting the date and exact time
• Discard this first portion of urine, but document date and time of voiding on the container label and test requisition as the "start" of the timed specimen
• Save all urine voided during the designated time period (usually 24 hours), including the portion voided at exact end of time period
• Document date and time of final voiding on the label and requisition as the "end" of the timed specimen
Refrigerate during and after collection

Transportation Instructions

• Refrigerate during and after collection
• Send entire 24-hour urine collection to laboratory for aliquot and pH adjustment

Stability

• Room Temperature: Unacceptable
• Refrigerated (preferred): 56 days
• Frozen: 365 days

Remarks

Patient Preparation:
5-HIAAcollections require that the following restrictions apply for at least 48 hours prior to the collection period, and during the collection period: Do not eat avocadoes, bananas, eggplant, kiwi fruit, pineapple, plums, tomatoes, chocolate, or walnuts. Substances in these foods may interfere with this test. Do not take medications that contain guaifenesin or reserpine.

CPT Codes

83497

Effective/Revised

11/20/2019

Clinical Significance

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