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Hepatitis A Antibody, IgM

Hepatitis A Antibody, IgM

Epic Mnemonic
Sunquest Mnemonic

LAB798
HAAIGM

Category

Chemistry

Methodology

Electrochemiluminescence immunoassay

Test Performance Schedule

Sunday - Saturday

Result Availability

Within 24 hours

Specimen Required

Container

Gold top (SST), Red top (serum), or Green top (lithium heparin) tube

Volume

Pref. Vol.: 1.0 mL serum or plasma
Min. Vol.: 0.5 mL serum or plasma

Collection Instructions

• Routine venipuncture

• Immediately after collection, gently invert tube 5-10 times

• Clot 30 minutes

• Promptly centrifuge 10 minutes

• If no gel barrier is present immediately transfer serum or plasma to a plastic tube and refrigerate

• Properly centrifuged gel barrier tube does not require transfer of serum or plasma to separate tube

Transportation Instructions

Refrigerated

Stability

Refrigerated: 5 days

Remarks

Medicare Medical Necessity Policy

Biotin, also referred to as Vitamin B7 or Vitamin H, can interfere with this test when taken in mega doses of 5mg (5000 mcg) or more. It is often promoted as a skin and hair beauty aid. Please ask your patients to refrain from taking Biotin or supplements containing Biotin for at least 24 hours before collecting specimens for lab testing.

https://biotinfacts.roche.com/

https://www.fda.gov/medicaldevices/safety/alertsandnotices/ucm586505.htm

CPT Codes

86709

Effective/Revised

03/30/2017

Clinical Significance

The hepatitis A virus is a RNA-containing virus that lacks an envelope. It belongs to the family of picornaviruses. Hepatitis A is the most common form of acute viral hepatitis. It is transmitted by the fecal-oral route. The disease has not been known to take a chronic course, nor does the virus persist in the organism.

 

An acute or recently acquired hepatitis A infection can be assumed if anti-HAV IgM antibodies are detected. Anti-HAV IgM antibodies can always be detected at the onset of the disease, and usually disappear 3 to 4 months later. Anti-HAV IgM can also be detected in some patients for a longer period of time, however. HAV IgM antibodies develop only very rarely after vaccination.

 

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