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Clinical Trial Opportunities
2002 South 11th Street, Niles, MI 49120, Phone: 269.687.0200
Start Date

Ages Eligible for Study: 18 Years and older
Genders Eligible for Study: Both
Accepts Healthy Volunteers: No

Inclusion criteria:
  • Diagnosis of type 2 diabetes mellitus prior to informed consent
  • Male and female patients on diet and exercise regimen who are drug-naive, defined as absence of any oral antidiabetic therapy for 12 weeks prior to randomization
  • HbA1c >=7.5% and <= 12% (>=58.5 mmol/mol and <=107.7 mmol/mol)
  • Body Mass Index (BMI) <= 45 kg/m2 at screening
Exclusion criteria:
  • Uncontrolled hyperglycemia with a glucose level >240 mg/dl (>13.3 mmol/L) after an overnight fast during placebo run-in and confirmed by a second laboratory measurement (not on the same day)
  • Any antidiabetic drug within 12 weeks prior to randomization
  • Impaired renal function, defined as estimated creatinine clearance rate (eCCr) <60 ml/min (Cockcroft-Gault formula) as determined during screening and/or run-in period
  • Contraindications to metformin according to the local label
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For further information participants can contact our Research Department at (269) 429-6604 ext. 1881 or (269) 932-1026

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    Lakeland Medical Center, St. Joseph  
    Lakeland Hospital, Niles  
    Lakeland Hospital, Watervliet  
    Center for Outpatient Services, St. Joseph  

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© 2014   Lakeland HealthCare   1234 Napier Avenue   St. Joseph, Michigan 49085   1-800-968-0115
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